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Literature summary for 3.1.1.3 extracted from

  • Jocken, J.W.; Smit, E.; Goossens, G.H.; Essers, Y.P.; van Baak, M.A.; Mensink, M.; Saris, W.H.; Blaak, E.E.
    Adipose triglyceride lipase (ATGL) expression in human skeletal muscle is type I (oxidative) fiber specific (2008), Histochem. Cell Biol., 129, 535-538.
    View publication on PubMedView publication on EuropePMC
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
triacylglycerol + H2O Homo sapiens ATGL plays a pivotal role for ATGL in intramuscular fatty acid handling, lipid storage and breakdown, overview, disturbances in skeletal muscle lipid turnover and lipolysis lead to accumulation of triacylglycerol and lipid intermediates in skeletal muscle, which plays an important role in the etiology of insulin resistance and type 2 diabetes mellitus diacylglycerol + a carboxylate
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 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
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Source Tissue

Source Tissue Comment Organism Textmining
adipose tissue expression of ATGL Homo sapiens
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skeletal muscle expression of ATGL, type I oxidative fiber-specific, immunohistochemic determination Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
triacylglycerol + H2O ATGL plays a pivotal role for ATGL in intramuscular fatty acid handling, lipid storage and breakdown, overview, disturbances in skeletal muscle lipid turnover and lipolysis lead to accumulation of triacylglycerol and lipid intermediates in skeletal muscle, which plays an important role in the etiology of insulin resistance and type 2 diabetes mellitus Homo sapiens diacylglycerol + a carboxylate
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 ?

Synonyms

Synonyms Comment Organism
adipose triglyceride lipase
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 Homo sapiens
ATGL
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 Homo sapiens