Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
triacylglycerol + H2O | Homo sapiens | ATGL plays a pivotal role for ATGL in intramuscular fatty acid handling, lipid storage and breakdown, overview, disturbances in skeletal muscle lipid turnover and lipolysis lead to accumulation of triacylglycerol and lipid intermediates in skeletal muscle, which plays an important role in the etiology of insulin resistance and type 2 diabetes mellitus | diacylglycerol + a carboxylate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adipose tissue | expression of ATGL | Homo sapiens | - |
skeletal muscle | expression of ATGL, type I oxidative fiber-specific, immunohistochemic determination | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
triacylglycerol + H2O | ATGL plays a pivotal role for ATGL in intramuscular fatty acid handling, lipid storage and breakdown, overview, disturbances in skeletal muscle lipid turnover and lipolysis lead to accumulation of triacylglycerol and lipid intermediates in skeletal muscle, which plays an important role in the etiology of insulin resistance and type 2 diabetes mellitus | Homo sapiens | diacylglycerol + a carboxylate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
adipose triglyceride lipase | - |
Homo sapiens |
ATGL | - |
Homo sapiens |