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Literature summary for 3.1.1.3 extracted from
- Hydrolysis of retinyl esters by pancreatic triglyceride lipase (2000), Biochemistry, 39, 4900-4906.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| cholate | activates carboxyl esterase activity | Mus musculus |  |
| cholate | activates carboxyl esterase activity | Rattus norvegicus | |
| taurocholate | activates carboxyl esterase activity | Mus musculus | |
| taurocholate | activates carboxyl esterase activity | Rattus norvegicus | |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| deoxycholate | no carboxyl esterase activity in presence of 2-hydroxy bile salts, such as deoxycholate and taurodeoxycholate | Mus musculus | |
| deoxycholate | no carboxyl esterase activity in presence of 2-hydroxy bile salts, such as deoxycholate and taurodeoxycholate | Rattus norvegicus | |
| taurodeoxycholate | no carboxyl esterase activity in presence of 2-hydroxy bile salts, such as deoxycholate and taurodeoxycholate | Mus musculus | |
| taurodeoxycholate | no carboxyl esterase activity in presence of 2-hydroxy bile salts, such as deoxycholate and taurodeoxycholate | Rattus norvegicus | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| retinyl palmitate + H2O | Mus musculus | - |
retinol + palmitate | - |
? | |
| retinyl palmitate + H2O | Rattus norvegicus | - |
retinol + palmitate | - |
? | |
| triolein + H2O | Mus musculus | - |
diolein + oleic acid | - |
? | |
| triolein + H2O | Rattus norvegicus | - |
diolein + oleic acid | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
enzyme-deficient CELKO and wild-type mice | - |
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partial from pancreas | Mus musculus |
| partial from pancreas | Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| pancreas | - |
Mus musculus | - |
| pancreas | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| retinyl palmitate + H2O | - |
Mus musculus | retinol + palmitate | - |
? | |
| retinyl palmitate + H2O | - |
Rattus norvegicus | retinol + palmitate | - |
? | |
| triolein + H2O | - |
Mus musculus | diolein + oleic acid | - |
? | |
| triolein + H2O | - |
Rattus norvegicus | diolein + oleic acid | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| pancreatic triglyceride lipase | - |
Mus musculus |
| pancreatic triglyceride lipase | - |
Rattus norvegicus |
| PTL | - |
Mus musculus |
| PTL | - |
Rattus norvegicus |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 23 | - |
assay at | Mus musculus |
| 23 | - |
assay at | Rattus norvegicus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7 | - |
assay at | Mus musculus |
| 7 | - |
assay at | Rattus norvegicus |
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Release 2023.1 (January 2023)
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