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Literature summary for 3.1.1.1 extracted from

  • Yang, Y.; Xu, R.; Ma, C.J.; Vlot, A.C.; Klessig, D.F.; Pichersky, E.
    Inactive methyl indole-3-acetic acid ester can be hydrolyzed and activated by several esterases belonging to the AtMES esterase family of Arabidopsis (2008), Plant Physiol., 147, 1034-1045.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.1.1

Cloned(Commentary)

Cloned (Comment) Organism
gene At3g10870 or AtMES17, phylogenetic analysis Arabidopsis thaliana

Protein Variants

Protein Variants Comment Organism
additional information incubating seedlings in the presence of indole-3-acetic acid methyl ester show that mes17 mutants hydrolyze only 40% of the indole-3-acetic acid methyl ester taken up by plants, whereas wild-type plants hydrolyze 100% of absorbed. Roots of Arabidopsis plants overexpressing AtMES17 show increased sensitivity to indole-3-acetic acid methyl ester but not to indole-3-acetic acid. Additionally, mes17 plants have longer hypocotyls and display increased expression of the auxin-responsive DR5:beta-glucuronidase reporter gene, suggesting a perturbation in indole-3-acetic acid homeostasis and/or transport Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
methyl 1H-indole-3-carboxylate + H2O Arabidopsis thaliana
-
 methanol + 1H-indole-3-carboxylate
-
 ?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana Q9SG92 gene At3g10870 or AtMES17
-

Source Tissue

Source Tissue Comment Organism Textmining
additional information AtMES17 is expressed at the highest levels in shoot apex, stem, and root, expression pattern of AtMES17, overview Arabidopsis thaliana
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root
-
 Arabidopsis thaliana
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seedling
-
 Arabidopsis thaliana
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shoot apex Arabidopsis thaliana
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stem
-
 Arabidopsis thaliana
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
methyl 1H-indole-3-carboxylate + H2O
-
 Arabidopsis thaliana methanol + 1H-indole-3-carboxylate
-
 ?

Synonyms

Synonyms Comment Organism
MeIAA esterase
-
 Arabidopsis thaliana
More the enzyme belongs to the methyl esterase family Arabidopsis thaliana

General Information

General Information Comment Organism
malfunction methyl 1H-indole-3-carboxylate exerts inhibitory activity on the growth of wild-type roots when applied exogenously. However, the roots of Arabidopsis plants carrying T-DNA insertions in the putative MeIAA esterase gene AtMES17 displays significantly decreased sensitivity to indole-3-acetic acid methyl ester compared with wild-type roots while remaining as sensitive to free indole.3.acetic acid as wild-type roots Arabidopsis thaliana
physiological function indole-3-acetic acid methyl ester, i.e. methyl 1H-indole-3-carboxylate, is an inactive form of indole-3-acetic acid, and the manifestations of indole-3-acetic acid methyl ester in vivo activity are due to the action of free indole-3-acetic acid that is generated from indole-3-acetic acid methyl ester upon hydrolysis by one or more plant esterases Arabidopsis thaliana