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Literature summary for 3.1.1.1 extracted from

  • Laguerre, C.; Sanchez-Hernandez, J.C.; Koehler, H.R.; Triebskorn, R.; Capowiez, Y.; Rault, M.; Mazzia, C.
    B-type esterases in the snail Xeropicta derbentina: an enzymological analysis to evaluate their use as biomarkers of pesticide exposure (2009), Environ. Pollut., 157, 199-207.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
4-nitrophenyl acetate an inhibition of CaE activity by 4-nitrophenyl acetate is observed at substrate concentration higher than 5 mM Xeropicta derbentina
chlorpyrifos-oxon CaE activity on 4-nitrophenyl valerate is more sensitive to chlorpyrifos-oxon than CaE activity determined by 4-nitrophenyl acetate and alpha-naphthyl acetate Xeropicta derbentina
dichlorvos CaE activities on 4-nitrophenyl acetate and alpha-naphthyl acetate are more sensitive to chlorpyrifos-oxon than CaE activity determined by 4-nitrophenyl valerate Xeropicta derbentina
eserine 20% inhibition of CaE activity at 2.5 mM eserine using 4-nitrophenyl valerate as a substrate Xeropicta derbentina
additional information not inhibited by carbamates Xeropicta derbentina

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.187
-
4-nitrophenyl valerate at 25°C Xeropicta derbentina
0.222
-
Alpha-naphthyl acetate at 25°C Xeropicta derbentina
0.98
-
4-nitrophenyl acetate at 25°C Xeropicta derbentina

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
Xeropicta derbentina 5829
-

Organism

Organism UniProt Comment Textmining
Xeropicta derbentina
-
-
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
192
-
crude extract, using 4-nitrophenyl acetate as substrate, at 25°C Xeropicta derbentina
437
-
crude extract, using 4-nitrophenyl valerate as substrate, at 25°C Xeropicta derbentina
1095
-
crude extract, using alpha-naphthyl acetate as substrate, at 25°C Xeropicta derbentina

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-nitrophenyl acetate + H2O
-
Xeropicta derbentina 4-nitrophenol + acetate
-
?
4-nitrophenyl valerate + H2O
-
Xeropicta derbentina 4-nitrophenol + valerate
-
?
alpha-naphthyl acetate + H2O
-
Xeropicta derbentina 1-naphthol + acetate
-
?

Synonyms

Synonyms Comment Organism
CaE
-
Xeropicta derbentina

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.0000224
-
using 4-nitrophenyl acetate as substrate, at 25°C Xeropicta derbentina dichlorvos
0.0000244
-
using 4-nitrophenyl valerate as substrate, at 25°C Xeropicta derbentina chlorpyrifos-oxon
0.0000298
-
using alpha-naphthyl acetate as substrate, at 25°C Xeropicta derbentina dichlorvos
0.002
-
using 4-nitrophenyl acetate as substrate, at 25°C Xeropicta derbentina chlorpyrifos-oxon
0.00321
-
using alpha-naphthyl acetate as substrate, at 25°C Xeropicta derbentina chlorpyrifos-oxon
0.012
-
using 4-nitrophenyl valerate as substrate, at 25°C Xeropicta derbentina dichlorvos