Application | Comment | Organism |
---|---|---|
medicine | intestinal carboxyesterase is the enzyme that activates doxazolidine carbamate prodrug Pentyl PABC-Doxaz. MCF-7 cells or U-373MG cells overexpressing the enzyme show dramatically reduced IC50 values for Pentyl PABC-Doxaz | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
expression in MCF-7 cell and U-373MG glioblastoma cell | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
isoform hiCE | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
intestine | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
pentyl PABC-Doxazolidine + H2O | - |
Homo sapiens | PABC-Doxazolidine + pentanol | - |
? |