Literature summary for 2.7.8.5 extracted from

Ticha, E.; Polakovicova, V.; Obernauerova, M.
Regulation of phosphatidylglycerolphosphate synthase in aerobic yeast Kluyveromyces lactis (2008), Folia Microbiol. (Praha), 53, 319-324.

Search for more literature for 2.7.8.5

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
mitochondrion	-	Kluyveromyces lactis	5739	-

Organism

Organism	UniProt	Comment	Textmining
Kluyveromyces lactis	Q874C6	aerobic yeast, strain JBD100	-

Posttranslational Modification

Posttranslational Modification	Comment	Organism
additional information	NetPhos 2.0 predicted motifs at residues Ser13, Thr9, and Tyr4 for protein kinase A and C (high score of 0.8), casein kinase I and II, glycogen-synthase kinase 3, Ca2+-calmodulin-dependent kinase II	Kluyveromyces lactis

Source Tissue

Source Tissue	Comment	Organism	Textmining
growth phase culture	similar mRNA levels in cells progressing from exponential to stationary phase when grown on glucose, glycerol and/or ethanol as C source and in presence or absence of phospholipid precursors myo-inositol and/or choline	Kluyveromyces lactis	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
0.00127	-	30% decrease in activity in cells grown in presence of myo-inositol (1 h, 75 microM), mitochondrial extracts	Kluyveromyces lactis
0.0018	-	mitochondrial extracts	Kluyveromyces lactis

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
CDP-1,2-diacyl-sn-glycerol + sn-glycerol 3-phosphate	20 min, 30°C, Mes-HCl pH 7, 1 mM Triton X-100, 0.3 mM MnCl2	Kluyveromyces lactis	phosphatidylglycerophosphate + CMP	-	?

Synonyms

Synonyms	Comment	Organism
PGS1	-	Kluyveromyces lactis
PGS1	KlPGS1: PGS1 gene from Kluyveromyces lactis	Kluyveromyces lactis
Pgs1p	-	Kluyveromyces lactis
phosphatidylglycerolphosphate synthase	-	Kluyveromyces lactis

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Release 2023.1 (January 2023)