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Literature summary for 2.7.7.9 extracted from

  • Li, M.; Chen, T.; Gao, T.; Miao, Z.; Jiang, A.; Shi, L.; Ren, A.; Zhao, M.
    UDP-glucose pyrophosphorylase influences polysaccharide synthesis, cell wall components, and hyphal branching in Ganoderma lucidum via regulation of the balance between glucose-1-phosphate and UDP-glucose (2015), Fungal Genet. Biol., 82, 251-263.
    View publication on PubMed
Search for more literature for 2.7.7.9

Cloned(Commentary)

Cloned (Comment) Organism
-
 Ganoderma lucidum

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.031
-
 alpha-D-glucose 1-phosphate pH 7.5, temperature not specified in the publication Ganoderma lucidum
0.774
-
 UDP-glucose pH 7.5, temperature not specified in the publication Ganoderma lucidum

Localization

Localization Comment Organism GeneOntology No. Textmining

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
56830
-
-
 Ganoderma lucidum

Organism

Organism UniProt Comment Textmining
Ganoderma lucidum
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
diphosphate + UDP-glucose
-
 Ganoderma lucidum UTP + alpha-D-glucose 1-phosphate
-
 r
UTP + alpha-D-glucose 1-phosphate
-
 Ganoderma lucidum diphosphate + UDP-glucose
-
 r

Subunits

Subunits Comment Organism
? x * 56830, calculated Ganoderma lucidum

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.21
-
 UDP-glucose pH 7.5, temperature not specified in the publication Ganoderma lucidum
33.11
-
 alpha-D-glucose 1-phosphate pH 7.5, temperature not specified in the publication Ganoderma lucidum

General Information

General Information Comment Organism
physiological function UGP gene silencing by RNAi results in changes in the levels of the intermediate metabolites D-glucose 1-phosphate and UDP-glucose. The compounds and structure of the cell wall in the silenced strains are also altered compared with those in the wild-type strains. The number of hyphal branches is also changed in the silenced strains. In an UGP over-expressing strain, the number of hyphal branches is influenced by UGP. Hyphal branching is regulated by a change in the cytosolic Ca2+ concentration, which is affected by the level of the intermediate metabolite Glc-1-P Ganoderma lucidum

kcat/KM [mM/s]

kcat/KM Value [1/mMs-1] kcat/KM Value Maximum [1/mMs-1] Substrate Comment Organism Structure
273
-
 UDP-glucose pH 7.5, temperature not specified in the publication Ganoderma lucidum
1067
-
 alpha-D-glucose 1-phosphate pH 7.5, temperature not specified in the publication Ganoderma lucidum