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Literature summary for 2.7.7.84 extracted from

  • Behera, A.; Kumar, M.; Lockey, R.; Mohapatra, S.
    2'-5' oligoadenylate synthetase plays a critical role in interferon-gamma inhibition of respiratory syncytial virus infection of human epithelial cells (2002), J. Biol. Chem., 277, 25601-25608.
    View publication on PubMed
Search for more literature for 2.7.7.84

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
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Source Tissue

Source Tissue Comment Organism Textmining
A-549 cell
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 Homo sapiens
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epithelial cell
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 Homo sapiens
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HEp-2 cell
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 Homo sapiens
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Synonyms

Synonyms Comment Organism
2'-5' oligoadenylate synthetase
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 Homo sapiens

General Information

General Information Comment Organism
malfunction cells transfected with 2–5 AS antisense oligonucleotides inhibit the antiviral effect of IFN-gamma Homo sapiens
physiological function 2'-5' oligoadenylate synthase plays a critical role in interferon-gamma inhibition of respiratory syncytial virus infection of human epithelial cells. Respiratory syncytial virus, RSV, associated with bronchiolitis and asthma, is resistant to the antiviral effects of type-I interferons, but not IFN-gamma, molecular mechanism involving the 2',5'-oligoadenylate synthetase, overview Homo sapiens