Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | P05055 | - |
- |
General Information | Comment | Organism |
---|---|---|
physiological function | polynucleotide phosphorylase contributes to the degradation of specific short mRNA fragments, the majority of which bind RNA chaperone Hfq and are derived from targets of sRNAs. The mRNA-derived fragments accumulate in the absence of polynucleotide phosphorylase or its exoribonuclease activity and interact with polynucleotide phosphorylase. Mutations in chaperone Hfq or in the seed pairing region of some sRNAs eliminate the requirement of polynucleotide phosphorylase for their stability | Escherichia coli |