Literature summary for 2.7.7.7 extracted from

Kranaster, R.; Drum, M.; Engel, N.; Weidmann, M.; Hufert, F.T.; Marx, A.
One-step RNA pathogen detection with reverse transcriptase activity of a mutated thermostable Thermus aquaticus DNA polymerase (2010), Biotechnol. J., 5, 224-231.

Search for more literature for 2.7.7.7

Application

Application	Comment	Organism
diagnostics	a mutated thermostable DNA polymerase, Taq M1, from Thermus aquaticus, that exhibits an increased reverse transcriptase activity, is therefore designated for one-step PCR pathogen detection using established real-time detection methods	Thermus aquaticus

Protein Variants

Protein Variants	Comment	Organism
additional information	generation of a mutated thermostable DNA polymerase, Taq M1, from Thermus aquaticus that exhibits an increased reverse transcriptase activity. The Taq polymerase mutant Taq M1 has similar PCR sensitivity and nuclease activity as the respective Taq wild-type DNA polymerase, but Taq M1 exhibits a significantly increased reverse transcriptase activity especially at high temperatures compared to the wild-type	Thermus aquaticus

Organism

Organism	UniProt	Comment	Textmining
Thermus aquaticus	-	-	-

Synonyms

Synonyms	Comment	Organism
DNA polymerase	-	Thermus aquaticus
reverse transcriptase	-	Thermus aquaticus
Taq polymerase	-	Thermus aquaticus

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Release 2023.1 (January 2023)