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Literature summary for 2.7.7.7 extracted from

  • Christov, P.P.; Petrova, K.V.; Shanmugam, G.; Kozekov, I.D.; Kozekova, A.; Guengerich, F.P.; Stone, M.P.; Rizzo, C.J.
    Comparison of the in vitro replication of the 7-(2-oxoheptyl)-1,N2-etheno-2-deoxyguanosine and 1,N2-etheno-2-deoxyguanosine lesions by Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4) (2010), Chem. Res. Toxicol., 23, 1330-1341.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
deoxynucleoside triphosphate + DNAn Saccharolobus solfataricus
-
diphosphate + DNAn+1
-
?
deoxynucleoside triphosphate + DNAn Saccharolobus solfataricus P2
-
diphosphate + DNAn+1
-
?

Organism

Organism UniProt Comment Textmining
Saccharolobus solfataricus
-
-
-
Saccharolobus solfataricus P2
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
deoxynucleoside triphosphate + DNAn
-
Saccharolobus solfataricus diphosphate + DNAn+1
-
?
deoxynucleoside triphosphate + DNAn translesion synthesis of the 7-(2-oxoheptyl)-1,N2-etheno-2'-deoxyguanosine lesion by the enzyme in 5'-TXG-3' and 5'-CXG-3' local sequence contexts is examined and compared to 1,N2-etheno-2'-deoxyguanosine lesions Saccharolobus solfataricus diphosphate + DNAn+1
-
?
deoxynucleoside triphosphate + DNAn
-
Saccharolobus solfataricus P2 diphosphate + DNAn+1
-
?
deoxynucleoside triphosphate + DNAn translesion synthesis of the 7-(2-oxoheptyl)-1,N2-etheno-2'-deoxyguanosine lesion by the enzyme in 5'-TXG-3' and 5'-CXG-3' local sequence contexts is examined and compared to 1,N2-etheno-2'-deoxyguanosine lesions Saccharolobus solfataricus P2 diphosphate + DNAn+1
-
?

Synonyms

Synonyms Comment Organism
DNA polymerase IV
-
Saccharolobus solfataricus
Dpo4
-
Saccharolobus solfataricus