Any feedback?
Literature summary for 2.7.7.7 extracted from
- Subunit protein-affinity isolation of Drosophila DNA polymerase epsilon catalytic subunit (2004), Protein Expr. Purif., 35, 248-256.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Mn2+ | inhibits 3'-5'-proofreading activity, thereby decreasing the fidelity of DNA replication by 50% | Drosophila melanogaster |  |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | synthesizes DNA processively in the presence of Mn2+ and Mg2+, optimal Mg2+ concentration is 3 mM | Drosophila melanogaster | |
| Mn2+ | synthesizes DNA processively in the presence of Mn2+ and Mg2+ | Drosophila melanogaster | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Drosophila melanogaster | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| DNA polymerase epsilon catalytic subunit | Drosophila melanogaster |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Drosophila melanogaster |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| DNA polymerase epsilon | - |
Drosophila melanogaster |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.5 | - |
- |
Drosophila melanogaster |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
