Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.7.7 extracted from

  • Doughty, M.B.; Aboudehen, K.; Anderson, G.; Li, K.; Moore, B.II; Poolson, T.
    Side-chain conformational restriction in template-competitive inhibitors of E. coli DNA polymerase I Klenow fragment: synthesis, structural characterization and inhibition activity (2004), Nucleosides Nucleotides Nucleic Acids, 23, 1751-1765.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
2-(4-azidophenacyl)thio-2'-deoxyadenosine 5'-triphosphate template-competitive DNA polymerase inhibitor Escherichia coli
alpha-(4-azidophenyl)-1,N6-etheno-dATP template-competitive DNA polymerase inhibitor Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Synonyms

Synonyms Comment Organism
DNA polymerase I
-
Escherichia coli

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
3.41
-
alpha-(4-azidophenyl)-1,N6-etheno-dATP
-
Escherichia coli