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Literature summary for 2.7.7.7 extracted from

  • Yakimovich, O.Y.; Alekseev, Y.I.; Maksimenko, A.V.; Voronina, O.L.; Lunin, V.G.
    Influence of DNA aptamer structure on the specificity of binding to Taq DNA polymerase (2003), Biochemistry (Moscow), 68, 228-235.
    View publication on PubMed

Application

Application Comment Organism
biotechnology thermostable polymerase used in PCR Thermus aquaticus
molecular biology thermostable polymerase used in PCR Thermus aquaticus

Inhibitors

Inhibitors Comment Organism Structure
aptamer nucleotide ligands of small size and unique three-dimensional structure, TQ21 family, presence of loop is necessary for inhibition Thermus aquaticus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
deoxynucleoside triphosphate + DNAn Thermus aquaticus
-
diphosphate + DNAn+1
-
?

Organism

Organism UniProt Comment Textmining
Thermus aquaticus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
deoxynucleoside triphosphate + DNAn
-
Thermus aquaticus diphosphate + DNAn+1
-
?