Inhibitors | Comment | Organism | Structure |
---|---|---|---|
16-oxoaphidicholin | - |
Tequatrovirus T4 | |
2-(p-n-Butylanilino)-2'-deoxyadenosine 5'-triphosphate | phage T4 enzyme inhibited with lower sensitivity than other members of the B family DNA polymerases | Tequatrovirus T4 | |
3-epiaphidicholine | - |
Tequatrovirus T4 | |
aphidicolin | phage T4 enzyme inhibited with lower sensitivity than other members of the B family DNA polymerases | Tequatrovirus T4 | |
Carbonyldiphosphonate | - |
Tequatrovirus T4 | |
diphosphate | analogs, phage T4 enzyme inhibited with lower sensitivity than other members of the B family DNA polymerases | Tequatrovirus T4 | |
additional information | inhibitor analysis of bacteriophage T4 DNA polymerase | Tequatrovirus T4 | |
N2-(p-n-butylphenyl)-2'-deoxyguanosine 5'-triphosphate | mechanism depends upon assay conditions, reversible competitive inhibition predominates | Tequatrovirus T4 |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
deoxynucleoside triphosphate + DNAn | Tequatrovirus T4 | - |
diphosphate + DNAn+1 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Tequatrovirus T4 | - |
Escherichia coli infected with | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
deoxynucleoside triphosphate + DNAn | - |
Tequatrovirus T4 | diphosphate + DNAn+1 | - |
? |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | - |
Tequatrovirus T4 | |
0.00054 | - |
2-(p-n-Butylanilino)-2'-deoxyadenosine 5'-triphosphate | pH 7.5, 30°C | Tequatrovirus T4 | |
0.00082 | - |
N2-(p-n-butylphenyl)-2'-deoxyguanosine 5'-triphosphate | pH 7.5, 30°C | Tequatrovirus T4 |