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Literature summary for 2.7.7.7 extracted from

  • Murakami, E.; Feng, J.Y.; Lee, H.; Hanes, J.; Johnson, K.A.; Anderson, K.S.
    Characterization of novel reverse transcriptase and other RNA-associated catalytic activities by human DNA polymerase gamma: importance in mitochondrial DNA replication (2003), J. Biol. Chem., 278, 36403-36409.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
catalytic subunits of wild-type and exonuclease-deficient mutant Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
Homo sapiens 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
deoxynucleoside triphosphate + DNAn Homo sapiens
-
diphosphate + DNAn+1
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
deoxynucleoside triphosphate + DNAn
-
Homo sapiens diphosphate + DNAn+1
-
?
deoxynucleoside triphosphate + DNAn polymerase gamma also has proofreading activity with an RNA template, reverse transcriptase activity and incorporates ribonucleotide triphosphates into a DNA primer Homo sapiens diphosphate + DNAn+1
-
?