Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.7.62 extracted from

  • Thompson, T.B.; Thomas, M.G.; Escalante-Semerena, J.C.; Rayment, I.
    Three-dimensional structure of adenosylcobinamide kinase/adenosylcobinamide phosphate guanylyltransferase from Salmonella typhimurium determined to 2.3 Å resolution (1998), Biochemistry, 37, 7686-7695.
    View publication on PubMed
Search for more literature for 2.7.7.62

Crystallization (Commentary)

Crystallization (Comment) Organism
X-ray structure determined to 2.3 A resolution, crystals grown by microbatch, enzyme is crystallized in space group C222(1) with unit cell dimensions of a : 96.4 A, b : 114.4 A, and c : 106.7 A Salmonella enterica subsp. enterica serovar Typhimurium

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
19770
-
 3 * 19770 Salmonella enterica subsp. enterica serovar Typhimurium

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
GTP + adenosylcobinamide phosphate Salmonella enterica subsp. enterica serovar Typhimurium
-
 diphosphate + adenosylcobinamide-GDP
-
 ?
GTP + adenosylcobinamide phosphate Salmonella enterica subsp. enterica serovar Typhimurium cobalamin biosynthesis, involved in de novo synthesis of vitamin B12 diphosphate + adenosylcobinamide-GDP
-
 ?

Organism

Organism UniProt Comment Textmining
Salmonella enterica subsp. enterica serovar Typhimurium
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Salmonella enterica subsp. enterica serovar Typhimurium

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GTP + adenosylcobinamide phosphate
-
 Salmonella enterica subsp. enterica serovar Typhimurium diphosphate + adenosylcobinamide-GDP
-
 ?
GTP + adenosylcobinamide phosphate cobalamin biosynthesis, involved in de novo synthesis of vitamin B12 Salmonella enterica subsp. enterica serovar Typhimurium diphosphate + adenosylcobinamide-GDP
-
 ?
additional information CobU is a bifunctional enzyme that has both kinase EC 2.7.1.156 and guanyltransferase EC 2.7.7.62 activities Salmonella enterica subsp. enterica serovar Typhimurium ?
-
 ?

Subunits

Subunits Comment Organism
trimer 3 * 19770 Salmonella enterica subsp. enterica serovar Typhimurium

Synonyms

Synonyms Comment Organism
adenosylcobinamide phosphate guanylyltransferase
-
 Salmonella enterica subsp. enterica serovar Typhimurium
CobU
-
 Salmonella enterica subsp. enterica serovar Typhimurium