Literature summary for 2.7.7.6 extracted from

Sharma, V.; Colson, P.; Giorgi, R.; Pontarotti, P.; Raoult, D.
DNA-dependent RNA polymerase detects hidden giant viruses in published databanks (2014), Genome Biol. Evol., 6, 1603-1610.

Search for more literature for 2.7.7.6

Application

Application	Comment	Organism
molecular biology	usage of enzyme RNAP to systematically decipher the black matter and identify giant viruses. As they lack ribosomal genes, these giant viruses are not part of the rDNA tree. A relevant alternative to rDNA for microbe identification are DNA-dependent RNA polymerase (RNAP) genes. They are more refractory to lateral gene transfers and usually present in a single copy in genomes, which avoids recombination and issues related to divergence between copies	Acanthamoeba polyphaga Mimivirus
molecular biology	usage of enzyme RNAP to systematically decipher the black matter and identify giant viruses. As they lack ribosomal genes, these giant viruses are not part of the rDNA tree. A relevant alternative to rDNA for microbe identification are DNA-dependent RNA polymerase (RNAP) genes. They are more refractory to lateral gene transfers and usually present in a single copy in genomes, which avoids recombination and issues related to divergence between copies	Phaeocystis globosa virus
molecular biology	usage of enzyme RNAP to systematically decipher the black matter and identify giant viruses. As they lack ribosomal genes, these giant viruses are not part of the rDNA tree. A relevant alternative to rDNA for microbe identification are DNA-dependent RNA polymerase (RNAP) genes. They are more refractory to lateral gene transfers and usually present in a single copy in genomes, which avoids recombination and issues related to divergence between copies	Phytophthora parasitica virus

Cloned(Commentary)

Cloned (Comment)	Organism
RNAPsubunit 2, RNAP2, DNA and amino acid sequence determination and analysis, detailed phylogenetic analysis and tree. Reconstruction of putative ancestral RNAP2 from the genome of eukaryote Hydra magnipapillata and Phytophthora parasitica using viral RNAP2, detection of megaviruse DNAs that are integrated into eukaryote genomes and misclassified	Acanthamoeba polyphaga Mimivirus
RNAPsubunit 2, RNAP2, DNA and amino acid sequence determination and analysis, detailed phylogenetic analysis and tree. Reconstruction of putative ancestral RNAP2 from the genome of eukaryote Hydra magnipapillata and Phytophthora parasitica using viral RNAP2, detection of megaviruse DNAs that are integrated into eukaryote genomes and misclassified	Phaeocystis globosa virus
RNAPsubunit 2, RNAP2, DNA and amino acid sequence determination and analysis, detailed phylogenetic analysis and tree. Reconstruction of putative ancestral RNAP2 from the genome of eukaryote Hydra magnipapillata and Phytophthora parasitica using viral RNAP2, detection of megaviruse DNAs that are integrated into eukaryote genomes and misclassified	Phytophthora parasitica virus

Organism

Organism	UniProt	Comment	Textmining
Acanthamoeba polyphaga Mimivirus	Q5UQ32 AND E3VZD2	subunit 6 and subunit beta	-
Phaeocystis globosa virus	R4THW7 AND R4TFI0	DNA-directed RNA polymerase II subunit RPB6 and subunit RPB10	-
Phytophthora parasitica virus	-	-	-

Synonyms

Synonyms	Comment	Organism
RNAP	-	Acanthamoeba polyphaga Mimivirus
RNAP	-	Phaeocystis globosa virus
RNAP	-	Phytophthora parasitica virus
RNAP2	-	Acanthamoeba polyphaga Mimivirus
RNAP2	-	Phaeocystis globosa virus
RNAP2	-	Phytophthora parasitica virus

General Information

General Information	Comment	Organism
additional information	DNA-dependent RNA polymerase (RNAP) genes are universal in microbes and conserved in giant viruses and may replace rDNA for identifying microbes	Acanthamoeba polyphaga Mimivirus
additional information	DNA-dependent RNA polymerase (RNAP) genes are universal in microbes and conserved in giant viruses and may replace rDNA for identifying microbes	Phaeocystis globosa virus
additional information	DNA-dependent RNA polymerase (RNAP) genes are universal in microbes and conserved in giant viruses and may replace rDNA for identifying microbes	Phytophthora parasitica virus

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Release 2023.1 (January 2023)