Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine | i.e. ECyd, TAS-106, a antitumor ribonucleoside that inhibits RNA polymerase, acts synergistically in inhibiting A-549 cancer cell growth and in tumor growth in vivo. The compound also inhibits the checkpoint-associated protein, the expression of Chk1 protein and the phosphorylation of Chk1 and Chk2, antitumour effects in combination with cisplatin, overview | Homo sapiens | |
3'-ethynylcytidine-5'-triphosphate | i.e. ECTP, competitive inhibition in the presence of isolated nuclei from FM3A mouse tumor cells | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
nucleus | - |
Homo sapiens | 5634 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
A-549 cell | - |
Homo sapiens | - |
carcinoma cell | - |
Homo sapiens | - |
lung cancer cell | - |
Homo sapiens | - |
oral cancer cell | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
RNA polymerase | - |
Homo sapiens |