Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Ctk1 | the kinase is required for the stability of the scaffold, but Ctk1 kinase activity is not required for the dissociation of basal transcription factors | Saccharomyces cerevisiae | |
additional information | the enzyme complex requires basal transcription factors, i.e. TFIID, TFIIA, TFIIH, and TFIIE, for complete processing of transitions from initiation to elongation, overview | Saccharomyces cerevisiae |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
phosphoprotein | the yeast Ctk1 kinase associates with elongation complexes and phosphorylates serine 2 in the YSPTSPS repeats of the RNApII large subunit Rpb1 C-terminal domain, a modification that is necessary for efficient recruitment of the Set2 methyltransferase to RNApII within transcribed regions and for coupling transcription to mRNA 3'-end processing, but Ser2 phosphorylation of the Rpb1 CTD does not regulate the 5' transitions. Ctk1 kinase activity is not required for the dissociation of basal transcription factors | Saccharomyces cerevisiae |
Synonyms | Comment | Organism |
---|---|---|
RNA polymerase II | - |
Saccharomyces cerevisiae |
RNAPII | - |
Saccharomyces cerevisiae |