Activating Compound | Comment | Organism | Structure |
---|---|---|---|
RNase P | required for Pol I and Pol III required | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | inactivation of RNase P, by knockdown of RNase P subunits Rpp21, Rpp29 or Rpp38 by RNA interference, reduces the level of nascent transcription by Pol I, and more considerably that of Pol III, e.g. causing marked reduction in transcription of rDNA by Pol I | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
nucleus | RNase P and Pol I are located at the promoter and coding region of rDNA | Homo sapiens | 5634 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
nucleoside triphosphate + RNAn | Homo sapiens | - |
diphosphate + RNAn+1 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HeLa cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
nucleoside triphosphate + RNAn | - |
Homo sapiens | diphosphate + RNAn+1 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Pol I | - |
Homo sapiens |
pol III | - |
Homo sapiens |
RNA polymerase I | - |
Homo sapiens |
RNA polymerase III | - |
Homo sapiens |