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Literature summary for 2.7.7.3 extracted from

  • Yoon, H.J.; Kang, J.Y.; Mikami, B.; Lee, H.H.; Suh, S.W.
    Crystal structure of phosphopantetheine adenylyltransferase from Enterococcus faecalis in the ligand-unbound state and in complex with ATP and pantetheine (2011), Mol. Cells, 32, 431-435.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
-
Enterococcus faecalis

Crystallization (Commentary)

Crystallization (Comment) Organism
ligand-unbound state and in complex with ATP and pantetheine, using 3.5 M sodium formate and 100 mM Tris-HCl (pH 8.5) Enterococcus faecalis

Inhibitors

Inhibitors Comment Organism Structure
pantetheine potent inhibitor Enterococcus faecalis

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ the enzyme contains a catalytic Mg2+ ion Enterococcus faecalis

Organism

Organism UniProt Comment Textmining
Enterococcus faecalis
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Enterococcus faecalis

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + pantetheine 4'-phosphate
-
Enterococcus faecalis diphosphate + 3'-dephospho-CoA
-
r

Subunits

Subunits Comment Organism
homohexamer x-ray crystallography Enterococcus faecalis

Synonyms

Synonyms Comment Organism
phosphopantetheine adenylyltransferase
-
Enterococcus faecalis
PPAT
-
Enterococcus faecalis