Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | P48561 | - |
- |
Synonyms | Comment | Organism |
---|---|---|
poly(A) RNA polymerase protein 1 | - |
Saccharomyces cerevisiae |
Trf5 | - |
Saccharomyces cerevisiae |
General Information | Comment | Organism |
---|---|---|
physiological function | nuclear RNA-dependent ATPase Mtr4 and either the nuclear non-canonical poly(A) polymerases, Trf4 or Trf5 assemble into a Trf4/5Air1/2/Mtr4 polyadenylation complex TRAMP. Disrupting the Mtr4/Trf interaction disrupts specific TRAMP and exosome functions, including small nucleolar RNA processing. A 20 amino acid peptide, residues 98-117 in the N-terminus of Trf5 is important for TRAMP complex formation | Saccharomyces cerevisiae |