Cloned (Comment) | Organism |
---|---|
expressed in 293T cells | Homo sapiens |
expressed in Escherichia coli BL21(DE3) pLysS cells | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | - |
Homo sapiens | 5737 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + RNA | Homo sapiens | - |
diphosphate + RNA(A)n | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
native tandem affinity column chromatography | Homo sapiens |
Sepharose column chromatography | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + RNA | - |
Homo sapiens | diphosphate + RNA(A)n | - |
? | |
ATP + RNA | Hs2 complexes have very little PAP activity, Hs2 also displays efficient poly(U) polymerase activity | Homo sapiens | diphosphate + RNA(A)n | - |
? | |
UTP + RNA | recombinant Cid1 shows a preference for UTP over ATP, the poly(U) polymerase activity of recombinant Cid1 out-competes its PAP activity under physiologically relevant conditions | Homo sapiens | diphosphate + RNA(U)n | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Cid1 | putative cytoplasmic PAP, in addition to having PAP activity, Cid1 possesses substantial poly(U) polymerase activity | Homo sapiens |
Hs2 | contains two PAP-associated domains and two nucleotidyl transferase motifs | Homo sapiens |
PAP | - |
Homo sapiens |
poly(A) polymerase | - |
Homo sapiens |
ZCCHC6 | - |
Homo sapiens |