Cloned (Comment) | Organism |
---|---|
PAPgamma(1-683C), a C-terminally truncated version of full length human PAPgamma with the same catalytic efficiency is expressed in Escherichia coli | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
5-epi-sisomycin | pH-dependent inhibition, non-competitive inhibitor for ATP | Homo sapiens | |
hygromycin B | pH-dependent inhibition | Homo sapiens | |
kanamycin A | pH-dependent inhibition | Homo sapiens | |
kanamycin B | pH-dependent inhibition | Homo sapiens | |
lividomycin A | pH-dependent inhibition | Homo sapiens | |
additional information | not inhibited by neamine | Homo sapiens | |
neomycin B | an increase in pH releases the neomycin B inhibitory effect on PAPgamma | Homo sapiens | |
paromomycin | pH-dependent inhibition | Homo sapiens | |
ribostamycin | pH-dependent inhibition | Homo sapiens | |
sisomicin | pH-dependent inhibition, non-competitive inhibitor for ATP | Homo sapiens | |
tobramycin | pH-dependent inhibition | Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | Mg2+ ions can release the inhibition of PAPgamma by aminoglycosides | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | the enzyme is responsible for the synthesis of the poly(A) tail at the 3'-end of eukaryotic mRNA | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + RNA | - |
Homo sapiens | diphosphate + RNA(A)n | - |
? | |
additional information | the enzyme is responsible for the synthesis of the poly(A) tail at the 3'-end of eukaryotic mRNA | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PAPgamma | - |
Homo sapiens |
poly(A) polymerase gamma | - |
Homo sapiens |