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Literature summary for 2.7.7.19 extracted from
- Human mitochondrial mRNAs are stabilized with polyadenylation regulated by mitochondria-specific poly(A) polymerase and polynucleotide phosphorylase (2005), J. Biol. Chem., 280, 19721-19727.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in Escherichia coli | Homo sapiens |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | hmtPAP knockdown mutant cells show decreased steady state levels of mtDNA-encoded proteins as well as deficient mitochondrial activities such as oxygen consumption rate | Homo sapiens |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrion | - |
Homo sapiens | 5739 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| by BD TALON Resin (zco, clontechClontech) or nickel-nitrilotriacetic acid-agarose (Qiagen) | Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| HeLa cell | - |
Homo sapiens | - |
Storage Stability
| Storage Stability | Organism |
|---|---|
| -70°C | Homo sapiens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + RNAn | - |
Homo sapiens | diphosphate + RNAn+1 | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PAP | - |
Homo sapiens |
| poly(A) polymerase | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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