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Literature summary for 2.7.7.19 extracted from

  • Ryner, L.C.; Takagaki, Y.; Manley, J.L.
    Multiple forms of poly(A) polymerases purified from HeLa cells function in specific mRNA 3-end formation (1989), Mol. Cell. Biol., 9, 4229-4238.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.7.19

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm 2 forms from nuclear fraction: NE PAPs I and II, one form from cytoplasmic fraction: S100 PAP Homo sapiens 5737
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nucleus 2 forms from nuclear fraction: NE PAPs I and II, one form from cytoplasmic fraction: S100 PAP Homo sapiens 5634
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Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ NE PAP I (isoenzyme from cytoplasmic fraction) and S100 PAP (isoenzyme from nuclear fraction): higher activity in presence of Mn2+ than in presence of Mg2+, NE PAP II: approximately equal levels in presence of Mn2+ and Mg2+ Homo sapiens
Mn2+ NE PAP I (isoenzyme from nuclear fraction) and S100 PAP (isoenzyme from cytoplasmic fraction): higher activity in presence of Mn2+ than in presence of Mg2+, NE PAP II: approximately equal levels in presence of Mn2+ and Mg2+ Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
50000 60000 enzymes NE PAP I and II, S100 PAP, sucrose density gradient sedimentation Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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 HeLa cells
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Homo sapiens
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 2 forms from nuclear fraction: NE PAP I and II, one form from cytoplasmic fraction: S100 PAP
-

Purification (Commentary)

Purification (Comment) Organism
2 forms from nuclear fraction: NE PAPs I and II, one form from cytoplasmic fraction: S100 PAP Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
HeLa cell
-
 Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + RNA primer required Homo sapiens diphosphate + RNA(A)n
-
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