Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.7.19 extracted from

  • Moss, B.; Rosenblum, E.N.; Gershowitz, A.
    Characterization of a polyriboadenylate polymerase from vaccinia virions (1975), J. Biol. Chem., 250, 4722-4729.
    View publication on PubMed
Search for more literature for 2.7.7.19

Inhibitors

Inhibitors Comment Organism Structure
Na+ 0.1 M; NaCl Vaccinia virus

Localization

Localization Comment Organism GeneOntology No. Textmining
viral nucleocapsid
-
 Vaccinia virus 19013
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ more active in presence of Mn2+ than Mg2+ Vaccinia virus
Mn2+ more active in presence of Mn2+ than Mg2+ Vaccinia virus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
35000
-
 1 * 51000 + 1 * 35000, SDS-PAGE Vaccinia virus
51000
-
 1 * 51000 + 1 * 35000, SDS-PAGE Vaccinia virus
80000
-
 sucrose density gradient sedimentation Vaccinia virus

Organism

Organism UniProt Comment Textmining
Vaccinia virus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Vaccinia virus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + RNA highly specific for ATP Vaccinia virus diphosphate + RNA(A)n
-
 ?
ATP + RNA primer required Vaccinia virus diphosphate + RNA(A)n
-
 ?
ATP + RNA minimum effective primer length is 4 to 6 nucleotides Vaccinia virus diphosphate + RNA(A)n
-
 ?

Subunits

Subunits Comment Organism
dimer 1 * 51000 + 1 * 35000, SDS-PAGE Vaccinia virus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.6
-
-
 Vaccinia virus

pH Range

pH Minimum pH Maximum Comment Organism
8 10 pH 8: about 40% of maximum activity, pH 10: about 50% of maximum activity Vaccinia virus