Cloned (Comment) | Organism |
---|---|
gene PRPS1, genomic structure, genotyping in European and Asian individuals | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
E43D | naturally occuring mutation causes the Rosenberg-Chutorian syndrome, the disease locus CMTX5 is situated on the chromosome band Xq21.32-q24 | Homo sapiens |
additional information | mutations in PRPS1 cause hereditary peripheral neuropathy with hearing loss and optic neuropathy, more | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-ribose 5-phosphate + ATP | Homo sapiens | biosynthesis of purines and pyrimidines | 5-phospho-alpha-D-ribose 1-diphosphate + AMP | - |
? | |
additional information | Homo sapiens | the phosphoribosyl pyrophosphate synthetase enzyme critical for nucleotide biosynthesis | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Homo sapiens | P60891 | gene PRPS1 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-ribose 5-phosphate + ATP | biosynthesis of purines and pyrimidines | Homo sapiens | 5-phospho-alpha-D-ribose 1-diphosphate + AMP | - |
? | |
additional information | the phosphoribosyl pyrophosphate synthetase enzyme critical for nucleotide biosynthesis | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
phosphoribosyl pyrophosphate synthase enzyme | - |
Homo sapiens |
phosphoribosyl pyrophosphate synthetase | - |
Homo sapiens |