Literature summary for 2.7.3.2 extracted from

Lue, Z.R.; Oh, S.H.; Zhou, S.S.; Zou, H.C.; Park, D.; Park, S.J.; Zhou, H.W.; Bhak, J.; Park, Y.D.; Zou, F.
Structural analysis and inhibitory Kinetics of brain type creatine kinase by sodium dodecyl sulfate (2010), Appl. Biochem. Biotechnol., 160, 831-842.

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Inhibitors

Inhibitors	Comment	Organism	Structure
SDS	strongly inhibits the CK-BB activity in a noncompetitive manner, although almost all the activity is eliminated by SDS CK-BB is never completely inactivated (4% to 5% activity is still sustained), regardless of increased incubation time or SDS concentration	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
cytoplasm	-	Homo sapiens	5737	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + creatine	-	Homo sapiens	ADP + creatine phosphate	-	?

Subunits

Subunits	Comment	Organism
homodimer	-	Homo sapiens

Synonyms

Synonyms	Comment	Organism
ATP: creatine N-phosphotransferase	-	Homo sapiens
brain creatine kinase	-	Homo sapiens
CK-BB	-	Homo sapiens

Cofactor

Cofactor	Comment	Organism	Structure
ATP	-	Homo sapiens

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
1.22	-	SDS	in 5 mM glycine-NaOH (pH 9.0), at 25°C	Homo sapiens

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Release 2023.1 (January 2023)