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Literature summary for 2.7.2.3 extracted from

  • Hwang, T.L.; Liang, Y.; Chien, K.Y.; Yu, J.S.
    Overexpression and elevated serum levels of phosphoglycerate kinase 1 in pancreatic ductal adenocarcinoma (2006), Proteomics, 6, 2259-2272.
    View publication on PubMed

Application

Application Comment Organism
medicine PGK1 is a potential biomarker and/or therapeutic target for pancreatic ductal adenocarcinoma Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
Homo sapiens 5737
-
nucleus
-
Homo sapiens 5634
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
45100
-
2-DE and MALDI-TOF MS Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
breast cancer cell moderate PGK1 expression Homo sapiens
-
colorectal cancer cell moderate PGK1 expression Homo sapiens
-
pancreatic ductal adenocarcinoma cell strong expression of PGK1 in more than 70% of the tumors, 7.7- to 11.7fold higher expression in the tumor tissues versus the adjacent nontumor samples Homo sapiens
-
serum levels of PGK1 are significantly higher in pancreatic ductal adenocarcinoma patients than in the control group, patients with gastric cancer have significantly elevated serum levels of PGK1 comparable to those observed in pancreatic ductal adenocarcinoma patients. In breast cancer patients levels of PGK1 are increased only slightly, and show no significant difference in colorectal cancer patients Homo sapiens
-

Synonyms

Synonyms Comment Organism
PGK 1
-
Homo sapiens
phosphoglycerate kinase 1
-
Homo sapiens