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Literature summary for 2.7.12.2 extracted from
- Isolation of MEK5 and differential expression of alternatively spliced forms (1995), J. Biol. Chem., 270, 28897-28902.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | isoform MEK5 beta is primarily cytosolic | Rattus norvegicus | 5829 | - |
| particle-bound | isoform MEK5 alpha | Rattus norvegicus | - |
- |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | Q62862 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | isoenzyme MEK5 beta | Rattus norvegicus | - |
| liver | enzyme MEK5 alpha | Rattus norvegicus | - |
| additional information | isoform MEK5 beta is ubiquitously distributed and primarily cytosolic. Isoform MEK5 alpha is expressed most highly in liver and brain and is particulate | Rattus norvegicus | - |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| More | alternative splicing results in a 50000 Da alpha and a 40000 Da beta isoform of MEK5 | Rattus norvegicus |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| dual specificity mitogen-activated protein kinase kinase 5 | - |
Rattus norvegicus |
| MEK5 | - |
Rattus norvegicus |
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