Literature summary for 2.7.12.2 extracted from

Moriguchi, T.; Kuroyanagi, N.; Yamaguchi, K.; Gotoh, Y.; Irie, K.; Kano, T.; Shirakabe, K.; Muro, Y.; Shibuya, H.; Matsumoto, K.; Nishida, E.; Hagiwara, M.
A novel kinase cascade mediated by mitogen-activated protein kinase kinase 6 and MKK3 (1996), J. Biol. Chem., 271, 13675-13679.

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Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
37000	-	x * 37000, calculation from nucleotide sequence	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P52564	-	-

Posttranslational Modification

Posttranslational Modification	Comment	Organism
phosphoprotein	the enzyme is phosphorylated and activated in vitro by TAK1	Homo sapiens

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + p38/MPK2 kinase	phosphorylates and specifically activates the p38/MPK2 subgroup of the mitogen-activated protein kinase superfamily	Homo sapiens	ADP + ?	-	?

Subunits

Subunits	Comment	Organism
?	x * 37000, calculation from nucleotide sequence	Homo sapiens

Synonyms

Synonyms	Comment	Organism
dual specificity mitogen-activated protein kinase kinase 6	-	Homo sapiens

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Release 2023.1 (January 2023)