Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Cd2+ | can partially substitue Mg2+ | eukaryota | |
Co2+ | can partially substitue Mg2+ | eukaryota | |
Mg2+ | dependent on, Mg2+ is the physiologic metal ion, other divalent cations are able to support nucleotide binding, but only Mn2+, Co2+, and Cd2+ can substitute Mg2+ in supporting the catalytic activity | eukaryota | |
Mn2+ | can partially substitue Mg2+ | eukaryota |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + a protein | eukaryota | - |
ADP + a phosphoprotein | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
eukaryota | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + a protein | - |
eukaryota | ADP + a phosphoprotein | - |
? | |
ATP + a protein | MKK1 phosphorylates and activates the MAP kinases ERK1 and ERK2 | eukaryota | ADP + a phosphoprotein | - |
? |
Synonyms | Comment | Organism |
---|---|---|
MAPK kinase-1 | - |
eukaryota |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | dependent on | eukaryota |