Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | activation is induced by epidermal growth factor tyrosine protein kinase and nucelar growth factor tyrosine protein kinase | eukaryota |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | MEK1, MEK2 | eukaryota | 5737 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | - |
eukaryota |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + a protein | eukaryota | - |
ADP + a phosphoprotein | - |
? | |
ATP + MAPK | eukaryota | MAPK activation | ADP + phosphorylated MAPK | - |
? | |
additional information | eukaryota | enzyme is part of mitogen-activated protein kinase pathways, crosstalk and regulation mechanism, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
eukaryota | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
phosphoprotein | activation by phosphorylation | eukaryota |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + a protein | - |
eukaryota | ADP + a phosphoprotein | - |
? | |
ATP + MAPK | MAPK activation | eukaryota | ADP + phosphorylated MAPK | - |
? | |
additional information | enzyme is part of mitogen-activated protein kinase pathways, crosstalk and regulation mechanism, overview | eukaryota | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
MAPK kinase | - |
eukaryota |
MAPKK | - |
eukaryota |
MEK1 | - |
eukaryota |
MEK2 | - |
eukaryota |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
eukaryota |