Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | expression of the Goodpasture antigen-binding protein is induced by tumor necrosis factor | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
DNA sequence determination and analysis, a TNF-responsive transcription unit that locates the enzyme in the signalling cascade of TNF, regulation of transcription, e.g. by tumor necrosis factor, via cooperation in a bidirectional transcription complex with the gene encoding the DNA polymerase kappa, NFkappaB, and a 140-bp promoter with a Sp1 site and a TATA-like element, promoter analysis, overview | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + [Goodpasture antigen-binding protein] | Homo sapiens | autophosphorylation via the enzyme's serine/threonine kinase activity that specifically targets a motif in the NC1 domain of the alpha3 chain of type IV collagen, the Good pasture autoantigen, the enzyme is involved in autoimmune processes and disease | ADP + [Goodpasture antigen-binding phosphoprotein] | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q9Y5P4 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HEK-293 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + [Goodpasture antigen-binding protein] | autophosphorylation via the enzyme's serine/threonine kinase activity that specifically targets a motif in the NC1 domain of the alpha3 chain of type IV collagen, the Good pasture autoantigen, the enzyme is involved in autoimmune processes and disease | Homo sapiens | ADP + [Goodpasture antigen-binding phosphoprotein] | - |
? | |
ATP + [Goodpasture antigen-binding protein] | autophosphorylation via the enzyme's serine/threonine kinase activity that specifically targets a motif in the NC1 domain of the alpha3 chain of type IV collagen, the Good pasture autoantigen | Homo sapiens | ADP + [Goodpasture antigen-binding phosphoprotein] | - |
? |
Synonyms | Comment | Organism |
---|---|---|
goodpasture-antigen-binding protein kinase | - |
Homo sapiens |
GPBP | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Homo sapiens |