Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | - |
Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + [actividin receptor] | Homo sapiens | - |
ADP + [actividin receptor] phosphate | - |
? | |
additional information | Homo sapiens | cyclin G2 mRNA is strongly up-regulated by Nodal and ALK7, Nodal and ALK7 decrease the expression of Skp1 and Skp2 and increase cyclin G2 levels. The antiproliferative effect of Nodal/ALK7 on ovarian cancer cells is in part mediated by cyclin G2, regulation, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
IOSE-397 cell | an ovarian surface epithelial cell line | Homo sapiens | - |
IOSE-398 cell | an ovarian surface epithelial cell line | Homo sapiens | - |
OV-2008 cell | an ovarian cancer cell line | Homo sapiens | - |
ovarian cancer cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + [actividin receptor] | - |
Homo sapiens | ADP + [actividin receptor] phosphate | - |
? | |
additional information | cyclin G2 mRNA is strongly up-regulated by Nodal and ALK7, Nodal and ALK7 decrease the expression of Skp1 and Skp2 and increase cyclin G2 levels. The antiproliferative effect of Nodal/ALK7 on ovarian cancer cells is in part mediated by cyclin G2, regulation, overview | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
activin receptor-like kinase 7 | - |
Homo sapiens |
ALK7 | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Homo sapiens |