Any feedback?
Literature summary for 2.7.11.27 extracted from
- Purification of an insulin-stimulated acetyl-CoA carboxylase kinase from rat epididymal adipose tissue (1995), Biochem. Soc. Trans., 23, 180S.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| Insulin | - |
Rattus norvegicus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| beta-Glycerophosphate | - |
Rattus norvegicus |  |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 53000 | - |
SDS-PAGE, two bands | Rattus norvegicus |
| 65000 | - |
SDS-PAGE, two bands | Rattus norvegicus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + [acetyl-CoA carboxylase] | Rattus norvegicus | involved in insulin dependent regulation of acetyl-CoA carboxylase in vivo | ADP + [acetyl-CoA carboxylase] phosphate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| adipose tissue | - |
Rattus norvegicus | - |
| epididymis | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + [acetyl-CoA carboxylase] | no increase in acetyl-CoA carboxylase activity | Rattus norvegicus | ADP + [acetyl-CoA carboxylase] phosphate | - |
? | |
| ATP + [acetyl-CoA carboxylase] | involved in insulin dependent regulation of acetyl-CoA carboxylase in vivo | Rattus norvegicus | ADP + [acetyl-CoA carboxylase] phosphate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| I-peptide kinase | highly specific for acetyl-CoA carboxylase, binds selectively to the dimeric form | Rattus norvegicus |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 10 | - |
beta-Glycerophosphate | - |
Rattus norvegicus | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
