Activating Compound | Comment | Organism | Structure |
---|---|---|---|
ATP | required | Rattus norvegicus | |
additional information | cAMP independent | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Rattus norvegicus | 5829 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | required | Rattus norvegicus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
90000 | - |
SDS-PAGE, two lighter bands at 40000 and 60000 Da detected | Rattus norvegicus |
160000 | 200000 | gel filtration | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + [acetyl-CoA carboxylase] | Rattus norvegicus | phosphorylates and inactivates acetyl-CoA carboxylase, (EC 6.4.1.2), and is therefore involved in regulation of long chain fatty acid synthesis | ADP + [acetyl-CoA carboxylase] phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
male Holtzman rats | - |
Purification (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.5 | - |
purified enzyme | Rattus norvegicus |
Storage Stability | Organism |
---|---|
-70°C, partially purified kinase preparation, stable for several months, highly purified kinase is very labile and loses activity within 5 days | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + [acetyl-CoA carboxylase] | inactivation of carboxylase | Rattus norvegicus | ADP + [acetyl-CoA carboxylase] phosphate | - |
? | |
ATP + [acetyl-CoA carboxylase] | phosphorylates and inactivates acetyl-CoA carboxylase, (EC 6.4.1.2), and is therefore involved in regulation of long chain fatty acid synthesis | Rattus norvegicus | ADP + [acetyl-CoA carboxylase] phosphate | - |
? |