Inhibitors | Comment | Organism | Structure |
---|---|---|---|
carteriosulfonic acid A | low micromolar inhibitor of GSK-3beta | Oryctolagus cuniculus | |
carteriosulfonic acid B | low micromolar inhibitor of GSK-3beta | Oryctolagus cuniculus | |
carteriosulfonic acid C | low micromolar inhibitor of GSK-3beta | Oryctolagus cuniculus | |
additional information | desacyl-carteriosulfonic acid shows no GSK-3beta inhibitory activity at concentrations up to 0.05 mM | Oryctolagus cuniculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Oryctolagus cuniculus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + beta-catenin | - |
Oryctolagus cuniculus | ADP + phosphorylated beta-catenin | - |
? | |
ATP + RRRPASVPPSPSLSRHSpSHQRR | - |
Oryctolagus cuniculus | ADP + ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
glycogen synthase kinase-3beta | - |
Oryctolagus cuniculus |
GSK-3beta | - |
Oryctolagus cuniculus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Oryctolagus cuniculus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0068 | - |
at 37°C | Oryctolagus cuniculus | carteriosulfonic acid B | |
0.0068 | - |
at 37°C | Oryctolagus cuniculus | carteriosulfonic acid C | |
0.0125 | - |
at 37°C | Oryctolagus cuniculus | carteriosulfonic acid A |