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Literature summary for 2.7.11.24 extracted from

  • Yanti, H.K.; Lee, M.; Kim, D.; Hwang, J.K.
    Inhibitory effect of panduratin A on c-Jun N-terminal kinase and activator protein-1 signaling involved in Porphyromonas gingivalis supernatant-stimulated matrix metalloproteinase-9 expression in human oral epidermoid cells (2009), Biol. Pharm. Bull., 32, 1770-1775.
    View publication on PubMed
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Activating Compound

Activating Compound Comment Organism Structure
Porphyromonas gingivalis supernatant
-
 Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
panduratin A
-
 Homo sapiens
SB203580
-
 Homo sapiens
SP600125
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + a protein Homo sapiens
-
 ADP + a phosphoprotein
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
phosphoprotein
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
KB cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + a protein
-
 Homo sapiens ADP + a phosphoprotein
-
 ?

Synonyms

Synonyms Comment Organism
c-Jun N-terminal kinase
-
 Homo sapiens
ERK1/2
-
 Homo sapiens
JNK
-
 Homo sapiens
MAP kinase
-
 Homo sapiens
mitogen-activated kinase
-
 Homo sapiens
p38
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens Porphyromonas gingivalis supernatant up-regulates ERK1/2 expression up
Homo sapiens Porphyromonas gingivalis supernatant up-regulates JNK expression up
Homo sapiens Porphyromonas gingivalis supernatant up-regulates p38 expression up