Cloned (Comment) | Organism |
---|---|
gene mpk4, gene expression profiling, overexpression of mpk4 leads to increased expression of the genes PR1 and PR2, encoding plant defense proteins, and of the ICS1 gene, encoding a salicylic acid biosynthetic enzyme | Arabidopsis thaliana |
Protein Variants | Comment | Organism |
---|---|---|
additional information | overexpression of MPK4 substrate MSK1 in wild-type plants leads to activated salicylic-dependent resistance, but does not interfere with induction of a defense gene by jasmonate | Arabidopsis thaliana |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | - |
Arabidopsis thaliana |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + MKS1 | Arabidopsis thaliana | MPK4 acts as a regulator of pathogen defense responses and is required for repression of salicylic acid-dependent resistance and for activation of jasmonate-dependent defense gene expression via MSK1, which interacts with the transcription factors WRKY25 and WRKY33 | ADP + phosphorylated MSK1 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Arabidopsis thaliana | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + MKS1 | MPK4 acts as a regulator of pathogen defense responses and is required for repression of salicylic acid-dependent resistance and for activation of jasmonate-dependent defense gene expression via MSK1, which interacts with the transcription factors WRKY25 and WRKY33 | Arabidopsis thaliana | ADP + phosphorylated MSK1 | - |
? | |
ATP + MKS1 | substrate of MPK4 | Arabidopsis thaliana | ADP + phosphorylated MSK1 | - |
? | |
ATP + WRKY25 | the transcription factor is an in vitro substrate of MPK4 | Arabidopsis thaliana | ADP + phosphorylated WRKY25 | - |
? | |
ATP + WRKY33 | the transcription factor is an in vitro substrate of MPK4 | Arabidopsis thaliana | ADP + phosphorylated WRKY33 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
MAP kinase 4 | - |
Arabidopsis thaliana |
MPK4 | - |
Arabidopsis thaliana |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Arabidopsis thaliana |