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Literature summary for 2.7.11.24 extracted from

  • Hunter, T.
    Protein kinases and phosphatases: the yin and yang of protein phosphorylation and signaling (1995), Cell, 80, 225-236.
    View publication on PubMed
Search for more literature for 2.7.11.24

Activating Compound

Activating Compound Comment Organism Structure
additional information the enzyme is activated by mitogens, activation is induced by epidermal growth factor tyrosine protein kinase and nucelar growth factor tyrosine protein kinase eukaryota

Localization

Localization Comment Organism GeneOntology No. Textmining
nucleus ERK1, ERK2 eukaryota 5634
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+
-
 eukaryota

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + a protein eukaryota
-
 ADP + a phosphoprotein
-
 ?
additional information eukaryota enzyme is part of mitogen-activated protein kinase pathways, crosstalk and regulation mechanism, overview ?
-
 ?

Organism

Organism UniProt Comment Textmining
eukaryota
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
phosphoprotein activation by phosphorylation eukaryota

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + a protein
-
 eukaryota ADP + a phosphoprotein
-
 ?
additional information enzyme is part of mitogen-activated protein kinase pathways, crosstalk and regulation mechanism, overview eukaryota ?
-
 ?

Synonyms

Synonyms Comment Organism
ERK1
-
 eukaryota
ERK2
-
 eukaryota
Fus3
-
 eukaryota
Kss1
-
 eukaryota
MAP kinase
-
 eukaryota
MAPK
-
 eukaryota

Cofactor

Cofactor Comment Organism Structure
ATP
-
 eukaryota