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Literature summary for 2.7.11.2 extracted from

  • Jung, G.S.; Jeon, J.H.; Choi, Y.K.; Jang, S.Y.; Park, S.Y.; Kim, S.W.; Byun, J.K.; Kim, M.K.; Lee, S.; Shin, E.C.; Lee, I.K.; Kang, Y.N.; Park, K.G.
    Pyruvate dehydrogenase kinase regulates hepatitis C virus replication (2016), Sci. Rep., 6, 30846.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.11.2

Application

Application Comment Organism
medicine blocking enzyme activity has therapeutic benefits against hepatitis C virus replication Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Homo sapiens 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + [pyruvate dehydrogenase (acetyl-transferring)] Homo sapiens
-
 ADP + [pyruvate dehydrogenase (acetyl-transferring)] phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
Huh-7.5 cell
-
 Homo sapiens
-
liver
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + [pyruvate dehydrogenase (acetyl-transferring)]
-
 Homo sapiens ADP + [pyruvate dehydrogenase (acetyl-transferring)] phosphate
-
 ?

Synonyms

Synonyms Comment Organism
PDK
-
 Homo sapiens
pyruvate dehydrogenase kinase
-
 Homo sapiens

General Information

General Information Comment Organism
physiological function the enzyme regulates hepatitis C virus replication Homo sapiens