Literature summary for 2.7.11.2 extracted from

Lan, J.; Lei, M.G.; Zhang, Y.B.; Wang, J.H.; Feng, X.T.; Xu, D.Q.; Gui, J.F.; Xiong, Y.Z.
Characterization of the porcine differentially expressed PDK4 gene and association with meat quality (2009), Mol. Biol. Rep., 36, 2003-2010.

Search for more literature for 2.7.11.2

Cloned(Commentary)

Cloned (Comment)	Organism
a cDNA library is constructed, the pGEM-T and pMD18-T vectors are used	Sus scrofa

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
mitochondrion	-	Sus scrofa	5739	-

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
46170	-	theoretical	Sus scrofa

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + [pyruvate dehydrogenase (acetyl-transferring)]	Sus scrofa	-	ADP + [pyruvate dehydrogenase (acetyl-transferring)] phosphate	-	?

Organism

Organism	UniProt	Comment	Textmining
Sus scrofa	C1IHT9	Yorkshire and Chinese indigenous breed Meishan pigs	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
heart	-	Sus scrofa	-
kidney	-	Sus scrofa	-
liver	-	Sus scrofa	-
ovary	-	Sus scrofa	-
pituitary gland	-	Sus scrofa	-
skeletal muscle	longissimus dorsal muscle	Sus scrofa	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + [pyruvate dehydrogenase (acetyl-transferring)]	-	Sus scrofa	ADP + [pyruvate dehydrogenase (acetyl-transferring)] phosphate	-	?

Synonyms

Synonyms	Comment	Organism
PDK4	-	Sus scrofa
pyruvate dehydrogenase kinase 4	-	Sus scrofa

Cofactor

Cofactor	Comment	Organism	Structure
ATP	-	Sus scrofa

pI Value

Organism	Comment	pI Value Maximum	pI Value
Sus scrofa	theoretical	-	7.19

Expression

Organism	Comment	Expression
Sus scrofa	PDK4 activity is increased in most tissues while starvation, exercise and diabetes mellitus	up

General Information

General Information	Comment	Organism
physiological function	regulation and controlling of the pyruvate dehydrogenase complex activity in skeletal muscles by phosphorylation	Sus scrofa

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Release 2023.1 (January 2023)