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Literature summary for 2.7.11.2 extracted from

  • Spriet, L.L.; Tunstall, R.J.; Watt, M.J.; Mehan, K.A.; Hargreaves, M.; Cameron-Smith, D.
    Pyruvate dehydrogenase activation and kinase expression in human skeletal muscle during fasting (2004), J. Appl. Physiol., 96, 2082-2087.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
additional information fasting largely increases PDK4 expression, increases PDK3 expression, but effects PDK2 and PDK1 only slightly in skeletal muscle, overview, peroxisome proliferator-activated receptor-alpha PPAR-alpha protein and forkhead homologue FKHR in rhabdomyosarcoma are putative transcriptional activators of the enzyme Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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female and male, isozyme PDK1-PDK4
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Source Tissue

Source Tissue Comment Organism Textmining
skeletal muscle isozyme PDK1-PDK4, with isozymes PDK2 and PDK4 being the most abundant, expression analysis in normal and fasted muscle Homo sapiens
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Synonyms

Synonyms Comment Organism
PDK
-
Homo sapiens