Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | farnesoid X receptor agonist GW4064 stimulates PDK4 expression in liver in vivo | Mus musculus | |
additional information | farnesoid X receptor agonists stimulate PDK4 expression in hepatocytes in vitro | Homo sapiens | |
additional information | glucocorticoids and farnesoid X receptor agonists, dexamethasone or WY14643, stimulate PDK4 expression in hepatoma cells in vitro | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Mus musculus | regulation of pyruvate dehydrogenase kinase expression by the farnesoid X receptor, mechanism | ? | - |
? | |
additional information | Homo sapiens | regulation of pyruvate dehydrogenase kinase expression by the farnesoid X receptor, mechanism | ? | - |
? | |
additional information | Rattus norvegicus | regulation of pyruvate dehydrogenase kinase expression by the farnesoid X receptor, mechanism | ? | - |
? | |
additional information | Mus musculus C57BL/6 | regulation of pyruvate dehydrogenase kinase expression by the farnesoid X receptor, mechanism | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Mus musculus | - |
C75BL/6 mice | - |
Mus musculus C57BL/6 | - |
C75BL/6 mice | - |
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
H4IIE cell | hepatoma cell line, determination of PDK4 expression level in presence or absence of farnesoid X receptor agonists | Rattus norvegicus | - |
hepatocyte | primary, determination of PDK4 expression level in presence or absence of farnesoid X receptor agonists | Homo sapiens | - |
hepatoma cell | - |
Rattus norvegicus | - |
liver | determination of PDK4 expression level in presence or absence of farnesoid X receptor agonists | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | regulation of pyruvate dehydrogenase kinase expression by the farnesoid X receptor, mechanism | Mus musculus | ? | - |
? | |
additional information | regulation of pyruvate dehydrogenase kinase expression by the farnesoid X receptor, mechanism | Homo sapiens | ? | - |
? | |
additional information | regulation of pyruvate dehydrogenase kinase expression by the farnesoid X receptor, mechanism | Rattus norvegicus | ? | - |
? | |
additional information | regulation of pyruvate dehydrogenase kinase expression by the farnesoid X receptor, mechanism | Mus musculus C57BL/6 | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PDK4 | - |
Mus musculus |
PDK4 | - |
Homo sapiens |
PDK4 | - |
Rattus norvegicus |
pyruvate dehydrogenase kinase | - |
Mus musculus |
pyruvate dehydrogenase kinase | - |
Homo sapiens |
pyruvate dehydrogenase kinase | - |
Rattus norvegicus |