Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q13555 | - |
- |
Homo sapiens | Q13557 | - |
- |
Rattus norvegicus | P08413 | - |
- |
Rattus norvegicus | P11275 | - |
- |
Synonyms | Comment | Organism |
---|---|---|
calcium-calmodulin-dependent protein kinase II | - |
Rattus norvegicus |
calcium-calmodulin-dependent protein kinase II | - |
Homo sapiens |
CaMKIIalpha | - |
Rattus norvegicus |
CaMKIIbeta | - |
Rattus norvegicus |
CaMKIIdeltaA | - |
Homo sapiens |
CaMKIIgammaB | - |
Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8 | - |
assay at | Rattus norvegicus |
8 | - |
assay at | Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | all CaMKII isoenzymes are implicated in a wide variety of cellular processes, which include a critical regulatory role in actin cytoskeletal assembly. All isoforms inhibit polymerization of actin in the order of decreasing effictivenes: CaMKIIbeta, CaMKIIgamma, CaMKIIdelta, CaMKIIalpha. Ca2+/CaM activation of all kinase isoforms produces a robust increase in actin polymerization that surpasses the rates of polymerization in the absence of kinase inhibition | Rattus norvegicus |
physiological function | all CaMKII isoenzymes are implicated in a wide variety of cellular processes, which include a critical regulatory role in actin cytoskeletal assembly. All isoforms inhibit polymerization of actin in the order of decreasing effictivenes: CaMKIIbeta, CaMKIIgamma, CaMKIIdelta, CaMKIIalpha. Ca2+/CaM activation of all kinase isoforms produces a robust increase in actin polymerization that surpasses the rates of polymerization in the absence of kinase inhibition. The beta isoform bundles actin filaments and sequesters actin monomers in an activity-dependent manner | Rattus norvegicus |
physiological function | all CaMKII isoenzymes are implicated in a wide variety of cellular processes, which include a critical regulatory role in actin cytoskeletal assembly. All isoforms inhibit polymerization of actin in the order of decreasing effictivenes: CaMKIIbeta, CaMKIIgamma, CaMKIIdelta, CaMKIIalpha. Ca2+/CaM activation of all kinase isoforms produces a robust increase in actin polymerization that surpasses the rates of polymerization in the absence of kinase inhibition. The delta isoform of CaMKII bundles F-actin filaments | Homo sapiens |
physiological function | all CaMKII isoenzymes are implicated in a wide variety of cellular processes, which include a critical regulatory role in actin cytoskeletal assembly. All isoforms inhibit polymerization of actin in the order of decreasing effictivenes: CaMKIIbeta, CaMKIIgamma, CaMKIIdelta, CaMKIIalpha. Ca2+/CaM activation of all kinase isoforms produces a robust increase in actin polymerization that surpasses the rates of polymerization in the absence of kinase inhibition. The gamma isoform induces a layered structure in filaments | Homo sapiens |