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Literature summary for 2.7.11.17 extracted from
- Ca2+/calmodulin-dependent protein kinase II-dependent remodeling of Ca2+ current in pressure overload heart failure (2008), J. Biol. Chem., 283, 25524-25532.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | CaMKII activity is significantly increased in heart failure | Homo sapiens |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| autocamtide-2-related inhibitory peptide | specific and potent CaMKII inhibitor | Homo sapiens |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | dependent on | Homo sapiens |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| cardiac myocyte | from heart failure | Homo sapiens | - |
| heart | - |
Homo sapiens | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Ca2+/calmodulin-dependent protein kinase II | - |
Homo sapiens |
| CaMKII | - |
Homo sapiens |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ATP | - |
Homo sapiens | |
| Calmodulin | dependent on | Homo sapiens | |
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Release 2023.1 (January 2023)
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