Cloned (Comment) | Organism |
---|---|
expressed in the LXSN retroviral expression vector M28248 | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
imatinib | downregulates CaMKIIgamma autophosphorylation/activation | Homo sapiens | |
KN-62 | - |
Homo sapiens | |
KN-93 | inhibits CaMKII activity by blocking its interaction with the Ca2+/calmodulin complex | Homo sapiens | |
additional information | not inhibited by AG490, JAK3 inhibitor, PP1, PD98059, U0126, SB203580, wortmannin, LY294002, c-Jun NH2-terminal kinase inhibitor II, Raf 1 inhibitor, pho kinase inhibitor, RO-31-8220, Go6983, cucurbitacin I, Gleevec, and AMPK inhibitor | Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | dependent on | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q13555 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
acute myeloid leukemia cell | - |
Homo sapiens | - |
chronic myeloid leukemia cell | - |
Homo sapiens | - |
DAUDI cell | - |
Homo sapiens | - |
DHL-4 cell | - |
Homo sapiens | - |
HL-60 cell | - |
Homo sapiens | - |
JURKAT cell | - |
Homo sapiens | - |
K-562 cell | - |
Homo sapiens | - |
Kasumi-1 cell | - |
Homo sapiens | - |
KCL-22 cell | - |
Homo sapiens | - |
KG-1 cell | - |
Homo sapiens | - |
myeloid leukemia cell | - |
Homo sapiens | - |
NB-4 cell | - |
Homo sapiens | - |
RAJI cell | - |
Homo sapiens | - |
Ramos cell | - |
Homo sapiens | - |
THP-1 cell | - |
Homo sapiens | - |
U-937 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + STAT3 | - |
Homo sapiens | ADP + phosphorylated STAT3 | - |
? | |
additional information | CaMKIIgamma is activated by autophosphorylation | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Ca2+/calmodulin-dependent protein kinase IIgamma | - |
Homo sapiens |
CaMKIIgamma | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Homo sapiens | |
Calmodulin | dependent on | Homo sapiens |